Isabela to Santa Cruz Ferry
Book your return from Isabela to Santa Cruz with selected boats, flexible changes, and local help if you are planning onward travel the same day.
A practical return leg if you need to reconnect with Santa Cruz plans, hotels, or onward transport.

Price
$38 one way
Duration
About 2h 15m
Departures
06:00 and 15:00
Departure Pier
Puerto Villamil
Arrival Pier
Gus Angermeyer
Check-in
45 min early
Book Isabela to Santa Cruz ferry
This route is especially useful if you need to reconnect with Santa Cruz plans, hotel check-in, or onward transport after leaving Isabela.
Why book this route with Galapagos Transfers?

Only the most reliable boats
We only book you on operators we trust and that do not overbook.

Individual front-facing seats
A more comfortable ride matters on open-water crossings.

Local help when you need it
Jenny is local and can help with route doubts or timing changes. WhatsApp Jenny
What to expect on this route
Early departures from Isabela
You depart from the Isabela pier near Puerto Villamil. The morning option leaves at 06:00, so early planning matters if you want the rest of the day back in Santa Cruz.
Arrival back into Puerto Ayora
You arrive at Gus Angermeyer pier in Puerto Ayora, on Santa Cruz island. That makes this the practical return leg if you still need to move across town or prepare for the next part of your trip.
Luggage and onward planning
The crossing is about 2 hours and 15 minutes. Bring the bags you need for normal inter-island travel and give yourself buffer time if you are planning anything important after arrival.
Isabela to Santa Cruz ferry FAQ
How early should I arrive in Isabela?
At least 45 minutes before departure. The early schedule makes it even more important to plan the transfer to the Isabela pier near Puerto Villamil in advance.
Is Puerto Villamil the same as Isabela?
Puerto Villamil is the main town on Isabela island. When travelers say they are departing from Isabela, they usually mean leaving from the Isabela pier near Puerto Villamil.
Is Puerto Ayora the same as Santa Cruz?
Puerto Ayora is the main town on Santa Cruz island. For ferry planning, Santa Cruz often means the Puerto Ayora area and the Gus Angermeyer pier.
Is this the best route if I have plans later in Santa Cruz?
Yes. This is the direct return route into Puerto Ayora, so it is the natural choice if you need to reconnect with Santa Cruz hotels, tours, or ground transport.
Can I book the early 06:00 departure online?
Yes. Use the booking form above to check the available schedule and secure seats before you are on the island trying to solve it at the last minute.
What if my plans change?
Message us as soon as possible. We are known for being much easier to work with on changes than leaving everything to local walk-up availability.

Need help planning the return?
If you are matching Isabela departure with plans in Santa Cruz, Jenny can help you pick the safer schedule and answer practical questions before you pay.
Or check our Frequently Asked Questions.
